In this episode of Arthritis Now, we talk with 2015 ANRF grant recipient, Susan Carpenter, PhD about her research into long non-coding RNA (lncRNA) and it’s potential to explain inflammation in rheumatoid arthritis (RA), Lupus and related autoimmune diseases.
Only three percent of the human genome actually codes for protein, or mRNA. So the question remains, what does the rest code for and how is that affecting inflammation in RA, Lupus and other autoimmune diseases? Dr. Carpenter’s foundational research is turning previously held beliefs in science of DNA and RNA on its head. lncRNA may hold the key to turning on and off inflammation in the body. Only time will tell if Dr. Carpenter’s research on lncRNA will provide the next major breakthrough in our understanding of the genome, but we’re learning a lot and the potential is truly exciting.
It is new thinking and new science like this that has the potential to make critical discoveries about the human body and the underlying mechanisms of disease. Science like that of Dr. Carpenters is what the Arthritis National Research Foundation looks for to push the field further to find new treatments, new explanations and cures for these terrible diseases.